Read case data


Clean and validate


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Example of data cleaning report generated by {cleanepi}
Example of data cleaning report generated by {cleanepi}

Aggregate and visulaize


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Simple analysis


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Access epidemiological delay distributions


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Definition of key time periods. From Xiang et al, 2021
Definition of key time periods. From Xiang et al, 2021

Figure 2

Video from the MRC Centre for Global Infectious Disease Analysis, Ep 76. Science In Context - Epi Parameter Review Group with Dr Anne Cori (27-07-2023) at https://youtu.be/VvpYHhFDIjI?si=XiUyjmSV1gKNdrrL
Video from the MRC Centre for Global Infectious Disease Analysis, Ep 76. Science In Context - Epi Parameter Review Group with Dr Anne Cori (27-07-2023) at https://youtu.be/VvpYHhFDIjI?si=XiUyjmSV1gKNdrrL

Figure 3

A schematic of the relationship of different time periods of transmission between an infector and an infectee in a transmission pair. Exposure window is defined as the time interval having viral exposure, and transmission window is defined as the time interval for onward transmission with respect to the infection time (Chung Lau et al., 2021).
A schematic of the relationship of different time periods of transmission between an infector and an infectee in a transmission pair. Exposure window is defined as the time interval having viral exposure, and transmission window is defined as the time interval for onward transmission with respect to the infection time (Chung Lau et al., 2021).

Figure 4

Serial intervals of possible case pairs in (a) COVID-19 and (b) MERS-CoV. Pairs represent a presumed infector and their presumed infectee plotted by date of symptom onset (Althobaity et al., 2022).
Serial intervals of possible case pairs in (a) COVID-19 and (b) MERS-CoV. Pairs represent a presumed infector and their presumed infectee plotted by date of symptom onset (Althobaity et al., 2022).

Figure 5

Fitted serial interval distribution for (a) COVID-19 and (b) MERS-CoV based on reported transmission pairs in Saudi Arabia. We fitted three commonly used distributions, Lognormal, Gamma, and Weibull distributions, respectively (Althobaity et al., 2022).
Fitted serial interval distribution for (a) COVID-19 and (b) MERS-CoV based on reported transmission pairs in Saudi Arabia. We fitted three commonly used distributions, Lognormal, Gamma, and Weibull distributions, respectively (Althobaity et al., 2022).

Figure 6

Serial interval of novel coronavirus (COVID-19) infections overlaid with a published distribution of SARS. (Nishiura et al., 2020)
Serial interval of novel coronavirus (COVID-19) infections overlaid with a published distribution of SARS. (Nishiura et al., 2020)

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Quantifying transmission


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Use delay distributions in analysis


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The four probability functions for the normal distribution (Jack Weiss, 2012)
The four probability functions for the normal distribution (Jack Weiss, 2012)

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Timeline for chain of disease reporting, the Netherlands. Lab, laboratory; PHA, public health authority. From Marinović et al., 2015
Timeline for chain of disease reporting, the Netherlands. Lab, laboratory; PHA, public health authority. From Marinović et al., 2015

Figure 5

R_{t} is a measure of transmission at time t. Observations after time t must be adjusted. ICU, intensive care unit. From Gostic et al., 2020
\(R_{t}\) is a measure of transmission at time \(t\). Observations after time \(t\) must be adjusted. ICU, intensive care unit. From Gostic et al., 2020

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